Klinische Forschergruppe

molecular pathology of cystic fibrosis
pseudomonas genomics
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Pseudomonas aeruginosa is an opportunistic pathogen for plants, animals and man. It is responsible for severe nosocomial infections and chronically colonizes lungs of patients with cystic fibrosis (CF) leading to morbidity and mortality. The genomes of the reference strain PAO1 www.pseudomonas.com and of several other strains have been sequenced completely, the results are invaluable for the research on pseudomonas genomics.


The Pseudomonas aeruguinosa Pangenome

The pangenome consists of the core genome which is common in all strains of the species and the ...

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Host-pathogen interactions


Virulence factors are the determinats for causing infectious diseases. Pseudomonads carry ...

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Microevolution in cystic fibrosis airways

The adaption to the habitat CF lung is necesary and shows evolution ...

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Population biology


There are hundreds of clones identified. Some are just found once and others ...

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Bioinformatics

Bioinformatics is the major tool of studying big amounts of data that scientist could not imagine 20 years ago ...

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Cystic fibrosis lung microbiome

There is not only one kind of bacteria present in the gut or the CF lung and all togehter are called the microbiome ...

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